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Gene Resources: From Transcription Factor Binding Sites to Function

Description:

This course describes how to obtain information about a human gene at all levels of the central dogma of life, genome, transcript and protein, and transcription factors regulating its expression. It also covers information about single nucleotide polymorphisms (SNPs) in the gene and which ones are known to be associated with disease.

To register, please visit the Registration Page.

Webpage Modified: September 4, 2009

Formats for Training:
Class
 
Class
 
       Dates Times Location
       2009/10/15 1:30-3:30 p.m. NIH Library Training Room, First Floor -- Registration Required 
      

Hands-on. Free. HHS staff only. For more information call 301-496-1080

       Objectives:
    I. Genomic and transcript related information
  • chromosome location
  • genomic, mRNA and protein sequence
  • alternative splice products and gene structure (exon-intron locations)
  • primers specific for the gene and spliced product
  • probes specific for the gene
  • known expressed sequences of the gene and their profiling by tissue, health state and developmental stage
  • SNPs in the gene and which ones are known to be associated with a phenotype
    II. Protein related information
  • protein function
  • pathways and downloading all genes in that pathway
  • phenotypes associated with mutations
  • interacting proteins and type of interaction
    III. Publications
  • publications documenting experiments that add to our understanding of the HRAS gene
    IV. Regulation of expression
  • known transcription factor binding sites
       Who Should Attend:  
Any NIH staff member with an interest in the topic
       Useful Handouts/Links:

This class is based on one of the mini-courses developed by the instructor Dr. Medha Bhagwat while working at NCBI

NCBI Mini-Courses


 

 

   
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