Contains over 388,000 chemical records; searchable by Name, Synonym, CAS Registry Number, Molecular formula, Classification Code, Locator Code, Structure, Toxicity and/or Physical properties.

Information for located clinical trials for a wide range of diseases and conditions. Covers thousands of trials sponsored by NIH, other government agencies, pharmaceutical companies, universities, foundations and organizations.

For a drug product that does not have a dissolution test method in the United States Pharmacopeia (USP), the FDA Dissolution Methods Database provides information on dissolution methods presently recommended by the Division of Bioequivalence, Office of Generic Drugs.

Delivers environmental, health and safety oriented data on thousands of pharmaceutical substances, drawing from US and European sources.

Covers over 17,000 drugs from entry into clinical trials through entry in the market place. Resources include the NLM search systems useful in searching fro a drug, and other NIH and government resources, such as FDA and CDC.

A peer-reviewed source of drugs to which breastfeeding mothers may be exposed. Includes data of maternal and infant levels of drugs, possible effects on breastfed infants, lactation and alternate drugs to consider. Search for information about US Food and Drug Administration approved brand name and generic drugs. Find labels for approved drug and generic products, therapueutically equivalent drug products, consumer information for drugs approved from 1998 on, all drugs with a specific active ingredient and view approval history.

Access to more than 70,000 uniquely cited references and 500,000 links to primary research on drugs, including analysis of drug and herbal interactions, off-label uses and dosing options, drug Identification, and patient information leaflets in up to 18 languages.

Provides summaries and detailed monographs for drugs, diseases, alternative medicine, toxicological managements, reproductive risks, and emergency care. The current NIH subscription includes:

Drug information databases:

DRUGDEX® System - dosage, pharmacokinetics, cautions, interactions, clinical applications, and comparative drug efficacy.
PDR Physicians' Desk Reference® - provides access to information found in the Physicians’ Desk Reference (PDR), the PDR for Nonprescription Drugs®, and the PDR for Ophthalmology® on approved data for prescription, nonprescription and ophthalmic pharmaceuticals by FDA
MARTINDALE – Electronic version of the Martindale textbook published by the Royal Pharmaceutical Society of Great Britain. Offers extensive information on international drug products. Especially useful when searching for European drugs, and can be searched by brand name or generic name.
Index Nominum – international drug directory of generic substances, drug trade names, synonyms, chemical formulas, therapeutic classes, and manufacturer information. Excellent resource for chemical information for pharmaceuticals.
DrugPoints® System (Drug Summary Information) - brief highlights of treatment, diagnosis, and key point information.
Alternative Medicine - includes monographs on herbal, vitamin, mineral, and other dietary supplements, based on scientific evidence as well has historical and common uses. Material is reviewed by members of both the alternative and traditional medical communities.

Toxicology:

POISINDEX - identifies the ingredients of over a million different commercial, pharmaceutical, and biological substances, including common household products, industrial products and chemicals, and pharmaceutical products. Each substance is linked to one or more management documents providing information on clinical effects, toxicity, and treatment.
Material Safety Data Sheets - Material Safety Data Sheets provide information about hazardous substances, including special precautions, handling procedures, and government regulations. The system includes more than a thousand MSDS issued by the U.S. Pharmacopeial Convention.
IDENTIDEX® System - facilitates the quick, accurate identification of unknown drugs by imprint code or slang term. A match is further confirmed by physical characteristic descriptions and photographs, and accompanied by ingredient and manufacturer data.
REPRORISK® Reproductive Risk Information - provides information on the reproductive risks of drugs, chemicals, and physical and environmental agents. Risks to females, males, and unborn children are discussed. REPRORISK includes: REPROTEXT® Reproductive Hazard Reference, REPROTOX® Reproduction Hazard Information (Reproductive Toxicology Center, Columbia Hospital for Women Medical Center, Washington, D.C.), Shepard’s Catalog of Teratogenic Agents developed by Dr. Thomas H. Shepard, TERIS Teratogen Information System developed by the University of Washington Complementary & Alternative Medicine
DISEASEDEX™ General Medicine Summary - supports disease management and treatment decisions in ambulatory and inpatient care settings. Covers all aspects of care including diagnosis, management highlights, prognosis, when to refer, follow-up, advising the patient, and prevention and screening.
IV INDEX System - provides information on drug-drug, food-drug, drug-disease, drug-ethanol, and drug-laboratory assay interactions, as well as IV compatibility. Both can be searched using a single substance or multiple substances and it features Trissel’s™ 2, the latest database from the ultimate authority on IV compatibility - Lawrence Trissel, MS, FASHP

Calaculators, Nomograms, and Other Clinical Tools:

Drug dosing calculators and nomograms, differential diagnosis lists, and other clinical tools can be accessed by pointing your cursor at the Main tab, then selecting Calculators.

Patient Education:

CareNotes is designed to assist healthcare professionals in educating patients and their families about their condition, treatment, follow-up care, and continuing health concerns, as well concise overviews of more than 700 frequently prescribed drugs. Documents are provided in Spanish as well as English, and are written at a 4th to 6th grade reading level.
The AltCareDex Alternative Medicine system includes consumer-appropriate information on dietary supplements (herbal medicines, vitamins, minerals, etc.) and complementary/alternative therapies.

Approved Drug Products with Therapeutic Equivalence Evaluations, known as the Orange Book, identifies drug products approved on the basis of safety and effectiveness.

Evidenced-based information on natural medicines. New interactions and safety concerns are added as soon as they are recognized, and evidenced-based Effectiveness Ratings, Safety ratings and Interaction ratings are raised or lowered based on new research. There are currently almost 1100 monographs on natural ingredients.

Provides information about complementary and alternative therapies. Information is created that is evidenced-based, consensus-based and peer reviewed.

The literature reviews are available in many medical and patient care disciplines covering drug information sectors; what is new in drug therapy, practice changing updates, general drug information for international, natural, pediatric and patient information.

AHFS has roots in the hospital formulary system. It includes; information on prescription, OC, ophthalmic, dermatologic drugs plus vitamins and vaccines, specific dosage and administration information, extensive off-label uses and dosing options, expanded and revised content, therapeutic recommendations supported from evidence, pharmacology and pharmacokinetics, preparations, chemistry and stability, interactions, advese reactions, cautions and toxicity.

Standards for UK pharmaceutical and medicinal substances. Includes veterinary monographs, test methods, infrared spectra and supplementary information.

The United States Pharmacopeia–National Formulary (USP–NF) is a book of public pharmacopeial standards. It contains standards for medicines, dosage forms, drug substances, excipients, medical devices, and dietary supplements.

Provides information and evidence to support health care decision making. It includes systematic reviews, clinical trials and more. Many of the reviews analyze the efficiency and adverse effect of pharmacological agents and provide a useful resource for completed or abandoned clinical trials. 

Core collection comprised of medical reference books, journals and clinics, MEDLINE, comprehensive drug information, peer reviewed clinical practice guidelines. The Drug portal includes generic and brand name drugs, investigational medications, neutraceuticals and nutritional products. The records include information on; indication/dosage, administration, contradictions/precautions, and interactions, adverse reactions, monitoring parameters, chemical structure and photographs.

Covers 46,000 fully searchable drug profiles with detailed information, including molecular structure. It provides data on which companies are developing with drugs, compare development of different drugs and track pharaceuticals of interest. Pipeline search tools allow conduction extensive searches by: disease, status/ stage of development, company name, therapeutic class, mechanism of action and biological target.

Pharmaprojects
Is an advanced desktop application (must be downloaded) that in addition to being able to search the drug information as shown with Pipeline, allowing to use the in-depth search functionality to identify all products that have been discontinued, launched or approved within a certain time period, or look for all drugs that are in Phase II trials in the US. Conduct chemical structure searches and analyze historical trends in R&D, track down a timeline of development history.

Pipeline's Research Support
The subscription includes free access to research support services for NIH staff. Professional analysts can conduct primary an secondary research on behalf of NIH clients and provide the answers to drug-specific questions.

Contains references to journal items focusing on biological and medical research findings, pharmacological studies and discoveries of new organisms.

A biomedical and pharmaceutical database. Subject coverage includes; drug research, pharmacology, pharmaceutics, pharmacy, drug side effects and interactions, toxicology, human medicine (clinical and experimental), basic biological sciences, biotechnology, biomedical, medical devices, engineering and insturmentation, health policy and management, pharmacoeconomics, public and occupational health, alternative and complementary medicine and more.

Online database of biomedial journal citations and abstracts.  PubMed is a service of the National Library of Medicine, includes over 18 million citations from MEDLINE® and additional life science journals for biomedical articles back to the 1950's. PubMed includes links to full text articles and other related resources.

Search for scientific, technical, medical, and social science literature from 14,000 journals. You can also search through 15 million patents. Scopus is updated daily and contains records with abstracts going back to 1966.

Information from over 5000 journals.